Prognostic Impact of Body Mass Index Stratified by Smoking Status in Patients With Esophageal Adenocarcinoma
Author(s) -
Harry H. Yoon,
Mark A. Lewis,
Qian Shi,
Maliha Khan,
Stephen D. Cassivi,
Robert B. Diasio,
Frank A. Sinicrope
Publication year - 2011
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2011.37.1260
Subject(s) - medicine , body mass index , overweight , obesity , hazard ratio , proportional hazards model , esophagectomy , obesity paradox , multivariate analysis , adenocarcinoma , univariate analysis , gastroenterology , esophageal cancer , cancer , confidence interval
Given that smoking affects body mass index (BMI) and survival, stratification by smoking status may be required to determine the true prognostic impact of BMI. Although obesity increases risk for developing esophageal adenocarcinoma (EAC), the prognostic influence of obesity and its potential modification by smoking status is unknown in this disease.
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