DIPSS Plus: A Refined Dynamic International Prognostic Scoring System for Primary Myelofibrosis That Incorporates Prognostic Information From Karyotype, Platelet Count, and Transfusion Status | Zendy

Naseema Gangat | Zendy; Domenica Caramazza | Zendy; Rakhee Vaidya | Zendy; Geeta George | Zendy; Kebede H. Begna | Zendy; Susan M. Schwager | Zendy; Daniel Van Dyke | Zendy; Curtis A. Hanson | Zendy; Wenting Wu | Zendy; Animesh Pardanani | Zendy; Francisco Cervantes | Zendy; Francesco Passamonti | Zendy; Ayalew Tefferi | Zendy

Open Access

DIPSS Plus: A Refined Dynamic International Prognostic Scoring System for Primary Myelofibrosis That Incorporates Prognostic Information From Karyotype, Platelet Count, and Transfusion Status

Author(s) -

Naseema Gangat,

Domenica Caramazza,

Rakhee Vaidya,

Geeta George,

Kebede H. Begna,

Susan M. Schwager,

Daniel Van Dyke,

Curtis A. Hanson,

Wenting Wu,

Animesh Pardanani,

Francisco Cervantes,

Francesco Passamonti,

Ayalew Tefferi

Publication year - 2010

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2010.32.2446

Subject(s) - medicine , myelofibrosis , international prognostic scoring system , prognostic model , oncology , karyotype , overall survival , platelet , bone marrow , myelodysplastic syndromes , biochemistry , chemistry , chromosome , gene

The Dynamic International Prognostic Scoring System (DIPSS) for primary myelofibrosis (PMF) uses five risk factors to predict survival: age older than 65 years, hemoglobin lower than 10 g/dL, leukocytes higher than 25 × 10(9)/L, circulating blasts ≥ 1%, and constitutional symptoms. The main objective of this study was to refine DIPSS by incorporating prognostic information from karyotype, platelet count, and transfusion status.

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