Open AccessGenome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors
Author(s) -
James N. Ingle,
Daniel J. Schaid,
Paul E. Goss,
Mohan Liu,
Taisei Mushiroda,
Judy-Anne W. Chapman,
Michiaki Kubo,
Gregory D. Jenkins,
Anthony Batzler,
Lois E. Shepherd,
Joseph L. Pater,
Liewei Wang,
Matthew J. Ellis,
Vered Stearns,
Daniel C. Rohrer,
Matthew P. Goetz,
Kathleen I. Pritchard,
David A. Flockhart,
Yusuke Nakamura,
Richard M. Weinshilboum
Publication year - 2010
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2010.28.5064
Subject(s) - single nucleotide polymorphism , genome wide association study , medicine , exemestane , breast cancer , oncology , genotyping , snp , case control study , genotype , bioinformatics , genetics , cancer , tamoxifen , biology , gene
We performed a case-control genome-wide association study (GWAS) to identify single nucleotide polymorphisms (SNPs) associated with musculoskeletal adverse events (MS-AEs) in women treated with aromatase inhibitors (AIs) for early breast cancer.
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