Serum Vascular Endothelial Growth Factor and Fibronectin Predict Clinical Response to High-Dose Interleukin-2 Therapy
Author(s) -
Marianna Sabatino,
Seunghee KimSchulze,
Monica C. Panelli,
David F. Stroncek,
Ena Wang,
Bret Taback,
Dae Won Kim,
Gail DeRaffele,
Zoltán Pós,
Francesco M. Marincola,
Howard L. Kaufman
Publication year - 2009
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2008.19.1106
Subject(s) - medicine , oncology , vascular endothelial growth factor , multivariate analysis , interleukin , immunology , cytokine , vegf receptors
High-dose interleukin-2 (IL-2) induces durable therapeutic responses in a small subset of patients with metastatic melanoma and renal cell carcinoma, but simple pretreatment predictors of response have not been identified.
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