Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma | Zendy

Mathieu P. Rodero | Zendy; Yannick Marie | Zendy; Mathieu Coudert | Zendy; Emmeline Blondet | Zendy; Karima Mokhtari | Zendy; Audrey Rousseau | Zendy; William Raoul | Zendy; Alain Carpentier | Zendy; Florian Sennlaub | Zendy; Philippe Déterre | Zendy; JeanYves Delattre | Zendy; Patrice Debré | Zendy; Marc Sanson | Zendy; Christophe Combadière | Zendy

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Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma

Author(s) -

Mathieu P. Rodero,

Yannick Marie,

Mathieu Coudert,

Emmeline Blondet,

Karima Mokhtari,

Audrey Rousseau,

William Raoul,

Alain Carpentier,

Florian Sennlaub,

Philippe Déterre,

JeanYves Delattre,

Patrice Debré,

Marc Sanson,

Christophe Combadière

Publication year - 2008

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2008.17.2833

Subject(s) - medicine , glioblastoma , gene , cx3cr1 , microglia , cancer research , oncology , chemokine , genetics , inflammation , biology , chemokine receptor

Few reliable prognostic molecular markers have been characterized for glioblastoma multiforme (GBM), considered the deadliest of human cancers. We hypothesized that genetic polymorphisms in chemokines and their receptors, which together control microglial cell mobilization, may influence survival.

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