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Amifostine Protects Against Cisplatin-Induced Ototoxicity in Children With Average-Risk Medulloblastoma
Author(s) -
Maryam Fouladi,
Murali Chintagumpala,
David M. Ashley,
Stewart J. Kellie,
Sridharan Gururangan,
Tim Hassall,
Lindsey Gronewold,
Clinton F. Stewart,
Dana Wallace,
Alberto Broniscer,
Gregory A. Hale,
Kimberly A. Kasow,
Thomas E. Merchant,
B. Morris,
Matthew J. Krasin,
Larry E. Kun,
James M. Boyett,
Amar Gajjar
Publication year - 2008
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2007.14.3974
Subject(s) - amifostine , ototoxicity , medicine , medulloblastoma , cisplatin , oncology , toxicity , chemotherapy , cancer research
To determine the role of amifostine as a protectant against cisplatin-induced ototoxicity in patients with average-risk (AR) medulloblastoma treated with craniospinal radiotherapy and four cycles of cisplatin-based, dose-intense chemotherapy and stem-cell rescue.

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