Interleukin-6, Cortisol, and Depressive Symptoms in Ovarian Cancer Patients | Zendy

Susan K. Lutgendorf | Zendy; Aliza Weinrib | Zendy; Frank J. Penedo | Zendy; Daniel W. Russell | Zendy; Koen DeGeest | Zendy; Erin S. Costanzo | Zendy; Patrick J. Henderson | Zendy; Sandra E. Sephton | Zendy; Nicolas Rohleder | Zendy; Joseph A. Lucci | Zendy; Steve W. Cole | Zendy; Anil K. Sood | Zendy; David M. Lubaroff | Zendy

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Interleukin-6, Cortisol, and Depressive Symptoms in Ovarian Cancer Patients

Author(s) -

Susan K. Lutgendorf,

Aliza Weinrib,

Frank J. Penedo,

Daniel W. Russell,

Koen DeGeest,

Erin S. Costanzo,

Patrick J. Henderson,

Sandra E. Sephton,

Nicolas Rohleder,

Joseph A. Lucci,

Steve W. Cole,

Anil K. Sood,

David M. Lubaroff

Publication year - 2008

Publication title -

journal of clinical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 10.482

H-Index - 548

eISSN - 1527-7755

pISSN - 0732-183X

DOI - 10.1200/jco.2007.14.1978

Subject(s) - medicine , depression (economics) , evening , ovarian cancer , cancer , endocrinology , gastroenterology , oncology , interleukin 6 , cytokine , physics , astronomy , economics , macroeconomics

Inflammatory processes have been implicated in the pathogenesis of both depression and cancer. Links between depressive symptoms, interleukin-6 (IL-6), and cortisol dysregulation have been demonstrated in cancer patients, but vegetative versus affective components of depression have been minimally examined. The objective of the current study was to examine associations between IL-6, diurnal cortisol rhythms, and facets of depression in epithelial ovarian cancer patients.

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