Specific Secondary Genetic Alterations in Mantle Cell Lymphoma Provide Prognostic Information Independent of the Gene Expression–Based Proliferation Signature
Author(s) -
Itziar Salaverría,
Andreas Zettl,
Sı́lvia Beà,
Vı́ctor Moreno,
Joan Valls,
Elena Hartmann,
German Ott,
George W. Wright,
Armando LópezGuillermo,
Wing C. Chan,
Dennis D. Weisenburger,
Randy D. Gascoyne,
Thomas M. Grogan,
Jan Delabie,
Elaine S. Jaffe,
Emili Montserrat,
Hans–Konrad Müller–Hermelink,
Louis M. Staudt,
Andreas Rosenwald,
Elı́as Campo
Publication year - 2007
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2006.08.4251
Subject(s) - cyclin d1 , cancer research , gene , gene expression profiling , locus (genetics) , mantle cell lymphoma , biology , comparative genomic hybridization , cell growth , chromosome , gene expression , medicine , cell cycle , lymphoma , oncology , genetics , immunology
To compare the genetic relationship between cyclin D1-positive and cyclin D1-negative mantle cell lymphomas (MCLs) and to determine whether specific genetic alterations may add prognostic information to survival prediction based on the proliferation signature of MCLs.
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