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CHOP Alone Compared With CHOP Plus Radiotherapy for Localized Aggressive Lymphoma in Elderly Patients: A Study by the Groupe d’Etude des Lymphomes de l’Adulte
Author(s) -
Christophe Bonnet,
Georges Fillet,
Nicolas Mounier,
G. Ganem,
Thierry Jo Molina,
Catherine Thiéblemont,
Christophe Fermé,
Bruno Quesnel,
C. Martin,
Christian Gisselbrecht,
Hervé Tilly,
Félix Reyes
Publication year - 2007
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2006.07.0722
Subject(s) - medicine , vincristine , chop , radiation therapy , international prognostic index , prednisone , chemotherapy , lymphoma , oncology , stage (stratigraphy) , aggressive lymphoma , chemoradiotherapy , adverse effect , surgery , cyclophosphamide , gastroenterology , rituximab , paleontology , biology
Chemoradiotherapy has been considered standard treatment for patients with limited-stage aggressive lymphoma on the basis of trials conducted before the introduction of the International Prognostic Index. To evaluate this approach in elderly patients with low-risk localized lymphoma, we conducted a trial comparing chemoradiotherapy with chemotherapy alone.

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