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Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical Outcome
Author(s) -
I. Jolanda M. de Vries,
Monique R. Bernsen,
W. Joost Lesterhuis,
Nicole M. Scharenborg,
S P Strijk,
MarieJeanne P. Gerritsen,
Dirk J. Ruiter,
Carl G. Figdor,
Cornelis J.A. Punt,
Gosse J. Adema
Publication year - 2005
Publication title -
journal of clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.482
H-Index - 548
eISSN - 1527-7755
pISSN - 0732-183X
DOI - 10.1200/jco.2005.06.478
Subject(s) - keyhole limpet hemocyanin , medicine , antigen , immunotherapy , melanoma , immunology , vaccination , t cell , cytotoxic t cell , dendritic cell , delayed hypersensitivity , immune system , cancer research , in vitro , biology , biochemistry
Tumor-specific immunomonitoring is essential to evaluate the efficacy of vaccination against cancer. In this study, we investigated the predictive value of the presence or absence of antigen-specific T cells in biopsies from delayed-type hypersensitivity (DTH) sites.

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