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Applying Radiomics to Predict Pathology of Postchemotherapy Retroperitoneal Nodal Masses in Germ Cell Tumors
Author(s) -
Jeremy Lewin,
Paul Dufort,
Jaydeep Halankar,
Martin O’Malley,
Michael Jewett,
Robert J. Hamilton,
Abha A. Gupta,
Armando J. Lorenzo,
Jeffrey Traubici,
Madhur Nayan,
Ricardo Leão,
Padraig Warde,
Peter Chung,
L. Cartwright,
Joan Sweet,
Aaron R. Hansen,
Ur Metser,
Philippe L. Bédard
Publication year - 2018
Publication title -
jco clinical cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.188
H-Index - 12
ISSN - 2473-4276
DOI - 10.1200/cci.18.00004
Subject(s) - radiomics , medicine , germ cell tumors , teratoma , fibrosis , magnetic resonance imaging , radiology , chemotherapy , pathology
After chemotherapy, approximately 50% of patients with metastatic testicular germ cell tumors (GCTs) who undergo retroperitoneal lymph node dissections (RPNLDs) for residual masses have fibrosis. Radiomics uses image processing techniques to extract quantitative textures/features from regions of interest (ROIs) to train a classifier that predicts outcomes. We hypothesized that radiomics would identify patients with a high likelihood of fibrosis who may avoid RPLND.

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