Relationship Between Objective Financial Burden and the Health-Related Quality of Life and Mental Health of Patients With Cancer

Purpose: The high and increasing costs of cancer care can lead to financial burden for patients and their families. However, no study has specifically examined the association between objective measures of financial burden and the health-related quality of life (HRQOL) and psychological health of patients with cancer.Methods: Data on patients with cancer were obtained from the 2010 to 2014 Medical Expenditure Panel Survey. High financial burden was defined as a ratio of annual family out-of-pocket health care expenditures to family income exceeding either 10% or 20%. Multivariable linear regressions were used to estimate the relationship between high financial burden and patient HRQOL, nonspecific psychological distress, and depressed mood.Results: Of 6,799 patients with cancer, 15% and 6% experienced high financial burden exceeding 10% and 20% of family income, respectively. Compared with those without high financial burden, patients with cancer with high financial burden were more likely to have significantly lower HRQOL and a greater tendency toward nonspecific psychological distress. Higher levels of financial burden were associated with lower HRQOL, with a stronger relationship observed with physical health than with mental health and a greater tendency toward nonspecific psychological distress. Depressed mood was not significantly associated with high financial burden.Conclusion: High financial burden among patients with cancer was significantly associated with lower HRQOL and poor mental health. Along with efforts to reduce health care costs for cancer survivors, additional interventions are necessary to ensure the HRQOL and psychological health of cancer survivors.