The University of Michigan Honest Broker: A Web-based Service for Clinical and Translational Research and Practice | Zendy

Andrew D. Boyd | Zendy; Paul Saxman | Zendy; D. A. Hunscher | Zendy; Kevin A. Smith | Zendy; T. D. Morris | Zendy; Michelle Kaston | Zendy; F. Bayoff | Zendy; Breanna Rogers | Zendy; Peter Hayes | Zendy; N. Rajeev | Zendy; Eva KlineRogers | Zendy; KA Eagle | Zendy; Daniel J. Clauw | Zendy; John F. Greden | Zendy; L. A. Green | Zendy; Brian D. Athey | Zendy

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The University of Michigan Honest Broker: A Web-based Service for Clinical and Translational Research and Practice

Author(s) -

Andrew D. Boyd,

Paul Saxman,

D. A. Hunscher,

Kevin A. Smith,

T. D. Morris,

Michelle Kaston,

F. Bayoff,

Breanna Rogers,

Peter Hayes,

N. Rajeev,

Eva KlineRogers,

KA Eagle,

Daniel J. Clauw,

John F. Greden,

L. A. Green,

Brian D. Athey

Publication year - 2009

Publication title -

journal of the american medical informatics association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.614

H-Index - 150

eISSN - 1527-974X

pISSN - 1067-5027

DOI - 10.1197/jamia.m2985

Subject(s) - collaboratory , translational research , interoperation , data sharing , workaround , clinical research , medicine , architecture , clinical trial , service (business) , documentation , computer science , world wide web , knowledge management , medical education , interoperability , alternative medicine , business , art , pathology , visual arts , programming language , marketing

For the success of clinical and translational science, a seamless interoperation is required between clinical and research information technology. Addressing this need, the Michigan Clinical Research Collaboratory (MCRC) was created. The MCRC employed a standards-driven Web Services architecture to create the U-M Honest Broker, which enabled sharing of clinical and research data among medical disciplines and separate institutions. Design objectives were to facilitate sharing of data, maintain a master patient index (MPI), deidentification of data, and routing data to preauthorized destination systems for use in clinical care, research, or both. This article describes the architecture and design of the U-M HB system and the successful demonstration project. Seventy percent of eligible patients were recruited for a prospective study examining the correlation between interventional cardiac catheterizations and depression. The U-M Honest Broker delivered on the promise of using structured clinical knowledge shared among providers to help clinical and translational research.

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