Disseminating Drug Prescribing Information: The Cox-2 Inhibitors Withdrawals | Zendy

Scott M. Strayer | Zendy; David C. Slawson | Zendy; Allen F. Shaughnessy | Zendy

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Disseminating Drug Prescribing Information: The Cox-2 Inhibitors Withdrawals

Author(s) -

Scott M. Strayer,

David C. Slawson,

Allen F. Shaughnessy

Publication year - 2006

Publication title -

journal of the american medical informatics association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.614

H-Index - 150

eISSN - 1527-974X

pISSN - 1067-5027

DOI - 10.1197/jamia.m2045

Subject(s) - valdecoxib , dissemination , drug withdrawal , medicine , drug , health professionals , medical emergency , computer science , health care , pharmacology , political science , telecommunications , rofecoxib , biochemistry , chemistry , law , cyclooxygenase , enzyme

This case study examined the recent withdrawal of valdecoxib to determine the timeliness of updates in commonly used information sources used by healthcare professionals. The method included assembling a purposive sample of 15 drug reference and warning systems that were then systematically monitored for several months after the withdrawal of valdecoxib to determine the time to update this information. These information sources were classified and described qualitatively. A time to diffusion curve was plotted and the average number of days to report the drug withdrawal or update reference databases was calculated. Only 2 of 15 information systems reported the drug withdrawal on the actual date of the FDA announcement. Institutional electronic textbooks took an average of 109.8 days (+/-14 days) to report the withdrawal. In addition, one pharma-sponsored dissemination source (Peerview Press) had not updated their information as of this publication.

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