Open AccessReconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria
Author(s) -
Thiago M. Venâncio,
L. Aravind
Publication year - 2009
Publication title -
journal of biology
Language(s) - English
Resource type - Journals
eISSN - 1478-5854
pISSN - 1475-4924
DOI - 10.1186/jbiol132
Subject(s) - actinobacteria , biology , computational biology , clade , transcriptional regulation , regulation of gene expression , evolutionary biology , gene regulatory network , genetics , gene , phylogenetics , transcription factor , gene expression , 16s ribosomal rna
Reconstruction of transcriptional regulatory networks of uncharacterized bacteria is a main challenge for the post-genomic era. Recent studies, including one in BMC Systems Biology, address this problem in the relatively underexplored actinobacteria clade, which includes major pathogenic and economically relevant taxa.
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