How to manage multiple pure ground-glass opacities?

Especially with the ongoing screening programmes for lung cancer, ground-glass opacities (GGO) are increasingly recognised on chest computed tomography (CT). Differential diagnosis includes inflammation, fibrosis or neoplasm in a very early stage. In some instances, multiple GGO lesions are detected. Specific management has not been established yet. In this retrospective study, characteristics and long-term follow-up were studied in patients presenting with multiple GGO.