Primary central nervous system lymphoma | Zendy

Tracy T. Batchelor | Zendy

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Primary central nervous system lymphoma

Author(s) -

Tracy T. Batchelor

Publication year - 2016

Publication title -

hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.321

H-Index - 91

eISSN - 1520-4391

pISSN - 1520-4383

DOI - 10.1182/asheducation-2016.1.379

Subject(s) - leptomeninges , primary central nervous system lymphoma , medicine , lymphoma , central nervous system , pathology , spinal cord , oncology , psychiatry

Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin lymphoma (NHL) confined to the brain, leptomeninges, eyes, or spinal cord. The majority of PCNSL cases occur in the immunocompetent host, the focus of this review. The prognosis of PCNSL is inferior to that of other NHL subtypes including other organ-specific subtypes of extranodal NHL. The 5- and 10-year survival proportions for PCNSL are 29.3% and 21.6%, respectively. The diagnosis and management of PCNSL differs from that of other primary brain cancers and NHL in other parts of the body.

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