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Congenital Malformations
Author(s) -
ChingHui Su,
Glen A. Rouse
Publication year - 2004
Publication title -
journal of diagnostic medical sonography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.138
H-Index - 16
eISSN - 8756-4793
pISSN - 1552-5430
DOI - 10.1177/8756479303261827
Subject(s) - medicine , holoprosencephaly , incidence (geometry) , craniofacial , renal agenesis , congenital malformations , trisomy , fetus , agenesis , duodenal atresia , pregnancy , pediatrics , obstetrics , surgery , atresia , kidney , genetics , physics , psychiatry , optics , biology
The incidence of multiple congenitalmalformations amid infants of mothers withinsulindependent diabetes mellitus (type I or IDDM) isbetween 6% and 12%. This is two to five timesthe incidence in nondiabetic mothers.Congenital malformations associated with IDDMinclude craniofacial defects, holoprosencephaly,cardiac defects, caudal regression syndrome,renal agenesis, gastrointestinal defects, and asingle umbilical artery. Unfortunately, thesemalformations are not exclusive to IDDMpregnancies. Many of the same pathologies are alsoseen in trisomy 13 fetuses.

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