Subcellular localization of blood group substances ABH in human salivary glands. | Zendy

M Cossu | Zendy; Agostino Riva | Zendy; M S Lantini | Zendy

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Subcellular localization of blood group substances ABH in human salivary glands.

Author(s) -

M Cossu,

Agostino Riva,

M S Lantini

Publication year - 1990

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/38.8.2365990

Subject(s) - immunogold labelling , antigen , golgi apparatus , immunohistochemistry , salivary gland , subcellular localization , monoclonal antibody , sublingual gland , antibody , submandibular gland , biology , pathology , microbiology and biotechnology , chemistry , immunology , endocrinology , medicine , cytoplasm , endoplasmic reticulum

We investigated the subcellular localization of ABH antigens in human submandibular, sublingual, and buccal glands by applying a post-embedding immunogold method using monoclonal antibodies specific for A, B, and H antigens. In most glands the immunoreactivity was usually restricted to mucous cells, in which only secretory granules and sometimes Golgi cisternae were specifically labeled. A and B antigens were demonstrated only in the glands of type A, B, and AB subjects, while H antigen was visualized in glands from individuals of all blood types. Moreover, differences were observed in the relative distribution of ABH antigens, depending on the type of gland.

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