Immunohistochemical localization of bursin in epithelial cells of the avian bursa of Fabricius.
Author(s) -
George I. Viamontes,
Tapan Audhya,
U. S. Babu,
Gideon Goldstein
Publication year - 1989
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/37.6.2470807
Subject(s) - bursa of fabricius , immunohistochemistry , antibody , pathology , staining , epithelium , reticular connective tissue , biology , antigen , microbiology and biotechnology , immunology , anatomy , spleen , medicine
Antibodies to the avian B-cell-differentiating hormone bursin (lysyl-histidyl-glycine amide) were raised in mice and rabbits by immunizing with bursin conjugates in Freund's adjuvant. Immunohistochemical staining with these bursin-specific antibodies was restricted to follicular and dendritic reticular epithelial cells of the bursa of Fabricius, and was not found in control avian tissues.
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