z-logo
open-access-imgOpen Access
Distribution of glucose-6-phosphatase activity in mice studied by in vitro whole-body autoradiography.
Author(s) -
Masashi Watanabe,
Hideyuki Goto,
Masaaki Matsushima,
Ryuichi Shimono,
Takashi Kihara
Publication year - 1983
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/31.12.6313801
Subject(s) - jejunum , duodenum , glucose 6 phosphatase , kidney , in vitro , phosphatase , alkaline phosphatase , medicine , medulla , endocrinology , specific activity , biology , distribution (mathematics) , cortex (anatomy) , small intestine , chemistry , enzyme , biochemistry , mathematical analysis , mathematics , neuroscience
The distribution of the glucose-6-phosphatase (G6Pase) activities was demonstrated by in vitro whole-body autoradiography. Relatively high activities were observed in the liver, kidney, and small intestine of mice. However, these organs did not exhibit uniform activity throughout. The activity of the liver was found heterogeneous, but that of the duodenum and jejunum were higher than for those of other parts of the intestine. G6Pase activity was higher in the cortex of the kidney than in the medulla. In addition to these observations, it was also found that the skeletal system had high radioactivity. These results were similar to those from biochemical experiments. This method of in vitro whole-body autoradiography would seem to be of value in studying macroscopic distributions of other enzyme activities in organs as well as in whole-body.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom