Immunohistochemical localization of kallikrein in human pancreas and salivary glands.
Author(s) -
T B Orstavik,
P Brandtzæg,
Kjell Nustad,
J V Pierce
Publication year - 1980
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/28.6.6156199
Subject(s) - kallikrein , excretory system , ductal cells , pancreas , immunohistochemistry , acinus , salivary gland , submandibular gland , pathology , sublingual gland , biology , chemistry , endocrinology , medicine , enzyme , biochemistry
The localization of kallikrein in human exocrine organs was studied with a direct immunofluorescence method. In the submandibular and parotid salivary glands, kallikrein was found apically in the striated duct cells whereas it was absent from the main excretory ducts or present only as a weak luminal rim. Kallikrein was not found in the acinar cells or in cells of the intercalated ducts. In the pancreas, kallikrein-specific fluorescence was seen in the granular portion of the acinar cells, whereas the islets of Langerhans and ductal cells were unstained.
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