Ultrastructural immunohistochemical localization of adrenocorticotropin and beta-lipotropin in the rat brain. | Zendy

G. Pelletier | Zendy

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Ultrastructural immunohistochemical localization of adrenocorticotropin and beta-lipotropin in the rat brain.

Author(s) -

G. Pelletier

Publication year - 1979

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/27.6.222836

Subject(s) - vesicle , ultrastructure , immunohistochemistry , chemistry , cell bodies , beta (programming language) , electron microscope , immunocytochemistry , endocrinology , biology , pathology , anatomy , central nervous system , biochemistry , medicine , physics , membrane , computer science , programming language , optics

In an attempt to identify the cells and organellel containing ACTH and beta-lipotropin in the rat brain, an immunocytochemical localization of these two peptides was performed at the electron microscopic level. Both ACTH and beta-lipotropin were localized in dense core vesicles of about 60-80 nm in diameter. Using serial sections, it has been possible to demonstrate that these peptides are contained not only in the same neuronal cell bodies, but also in the same dense core vesicles.

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