Immunohistochemical characterization of monolayer cell cultures of embryonic chicken pancreas and measurement of somatostatin release. | Zendy

Nicholas Barden | Zendy; Donald Dubé | Zendy; Jean-Pierre Côté | Zendy; Rachel Leclerc | Zendy; G. Pelletier | Zendy

Open Access

Immunohistochemical characterization of monolayer cell cultures of embryonic chicken pancreas and measurement of somatostatin release.

Author(s) -

Nicholas Barden,

Donald Dubé,

Jean-Pierre Côté,

Rachel Leclerc,

G. Pelletier

Publication year - 1979

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/27.5.479556

Subject(s) - somatostatin , immunohistochemistry , glucagon , pancreas , radioimmunoassay , embryonic stem cell , medicine , endocrinology , biology , cell , hormone , chemistry , pancreatic polypeptide , secretion , microbiology and biotechnology , biochemistry , gene

Monolayer cell cultures of embryonic chicken pancreas contain functionally active insulin, glucagon and somatostatin-containing cells as evidenced by immunohistochemical and radioimmunoassay techniques. Hormone release is in relation to the number of each cell type present and responds to known specific secretory stimuli. The relatively high numbers of D-cells and amounts of immunoreactive somatostatin released by this preparation makes this system a suitable model for studies of somatostatin function and secretion.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research