Ultrastructural localization of pancreatic polypeptide in the F cell of the dog pancreas.
Author(s) -
Marie H. Greider,
D J Gersell,
Ronald L. Gingerich
Publication year - 1978
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/26.12.366015
Subject(s) - pancreatic polypeptide , pancreas , ultrastructure , cell , islet , immunocytochemistry , pathology , staining , chemistry , immunohistochemistry , biology , microbiology and biotechnology , anatomy , biochemistry , endocrinology , medicine , glucagon , insulin , hormone
The F cell of the dog pancreas has been identified as the specific cell type containing pancreatic polypeptide. This localization of pnacreatic polypeptide was accomplished by immunocytochemical staining of ultrathin sections and direct electron microscopic identification. Verification of the specificity of the reaction was obtained by blocking experiments on serial sections of the same cell. It is proposed that the name F cell be used for defining in all species the islet cell that contains pancreatic polypeptide.
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