Open AccessReversible Sensorineural Hearing Loss Resulting from Hypertrophic Pachymeningitis in Systemic Lupus Erythematosus: A Case Report
Author(s) -
Bullington Molly,
Davies George,
MacDonald C. Bruce
Publication year - 2019
Publication title -
oto open
Language(s) - English
Resource type - Journals
ISSN - 2473-974X
DOI - 10.1177/2473974x19865526
Subject(s) - medicine , hydroxychloroquine , hearing loss , sensorineural hearing loss , tinnitus , lumbar puncture , vertigo , surgery , thrombocytopenic purpura , dermatology , pediatrics , cerebrospinal fluid , disease , covid-19 , psychiatry , infectious disease (medical specialty) , audiology , platelet
S ystemic lupus erythematosus (SLE) is a common autoimmune condition targeting various organ systems throughout the body. SLE is frequently undiagnosed or misdiagnosed due to its wide range of symptoms. Hypertrophic pachymeningitis (HP), defined by inflammation of the dura mater, is a rare clinical condition that can manifest with a variety of symptoms, such as headache and multiple cranial neuropathies. HP may be idiopathic or associated with a concurrent disease, typically an autoimmune disorder. Correlation between HP and SLE is rare, with few reports in the literature. Review of the literature identified a single report from Japan of SLE associated with HP, manifesting as profound hearing loss. We present a patient with SLE-related HP who experienced sudden unilateral sensorineural hearing loss (SNHL) with associated vertigo and an unexpectedly favorable response to treatment.