Open AccessInvasive Sino‐orbital‐skull Base Aspergillosis Progressing from Aspergillus Ball of Maxillary Sinus: A Case Report
Author(s) -
Huang Qi,
Zhao Kan,
Wu Zhenhua
Publication year - 2017
Publication title -
oto open
Language(s) - English
Resource type - Journals
ISSN - 2473-974X
DOI - 10.1177/2473974x17726987
Subject(s) - medicine , aspergillosis , surgery , exophthalmos , superior orbital fissure , orbit (dynamics) , anterior cranial fossa , paranasal sinuses , magnetic resonance imaging , maxillary sinus , sinusitis , skull , radiology , cavernous sinus , immunology , engineering , aerospace engineering
Aspergillus diseases of the sinuses are a diverse group of diseases with subtle presentations such as allergic fungal sinusitis and aspergillus ball (AB) to localized invasive aspergillosis and fulminant form. Usually, localized disease first occurs in the sinuses and spreads to adjacent structures, such as orbital and cranial. The specific diagnosis of invasive sino-orbital-skull base aspergillosis (ISOSA) is often delayed, as it may mimic a number of inflammatory conditions and malignancies. Effective treatment requires early diagnosis because immediate surgical debridement and antifungal therapy are highly recommended. However, complete cure is rarely achieved. Here we present a rare and typical case of ISOSA demonstrating orbital apex syndrome arising from the AB of maxillary. This case was approved by the Ningbo Medical Center Lihuili Eastern Hospital institutional review board and ethics committee.