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Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans
Author(s) -
Christopher L. Averill,
Ritvij Satodiya,
J. Cobb Scott,
Kristen M. Wrocklage,
Brian C. Schweinsburg,
Lynnette A. Averill,
Teddy J. Akiki,
Timothy Amoroso,
Steven M. Southwick,
John H. Krystal,
Chadi G. Abdallah
Publication year - 2017
Publication title -
chronic stress
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.209
H-Index - 14
ISSN - 2470-5470
DOI - 10.1177/2470547017744538
Subject(s) - neuroimaging , hippocampal formation , beck depression inventory , psychology , beck anxiety inventory , magnetic resonance imaging , depression (economics) , hippocampus , posttraumatic stress , anxiety , major depressive disorder , dentate gyrus , clinical psychology , psychiatry , medicine , amygdala , neuroscience , macroeconomics , economics , radiology
Two decades of human neuroimaging research have associated volume reductions in the hippocampus with posttraumatic stress disorder. However, little is known about the distribution of volume loss across hippocampal subfields. Recent advances in neuroimaging methods have made it possible to accurately delineate 10 gray matter hippocampal subfields. Here, we apply a volumetric analysis of hippocampal subfields to data from a group of combat-exposed Veterans.

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