Approach to three-dimensional mapping of quantitative histochemical measurements applied to studies of the cochlear nucleus.
Author(s) -
Donald A. Godfrey,
F M Matschinsky
Publication year - 1976
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/24.6.781128
Subject(s) - computer science , sampling (signal processing) , sample (material) , nucleus , process (computing) , neuroscience , biology , chemistry , computer vision , chromatography , filter (signal processing) , operating system
After reviewing the historical development of some procedures for localizing quantitative histochemical measurements, an approach is presented which combines some aspects of these procedures to make possible a permanent, objective record of the location of each sample. The method further allows direct comparisons to be made with drawings of other nearby sections during the process of sampling. Illustrations are given of various applications to a study of the cochlear nucleus. A particular benefit of the approach is to facilitate comparison of chemical with anatomical and physiologic data.
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