Open AccessEuropean Stroke Organisation expedited recommendation for the use of short-term dual antiplatelet therapy early after minor stroke and high-risk TIA
Author(s) -
Jesse Dawson,
Áine Merwick,
Alastair Webb,
Martin Dennis,
Julia Ferrari,
Ana Catarina Fonseca
Publication year - 2021
Publication title -
european stroke journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 16
eISSN - 2396-9881
pISSN - 2396-9873
DOI - 10.1177/23969873211000877
Subject(s) - medicine , aspirin , clopidogrel , minor stroke , ticagrelor , stroke (engine) , guideline , ischaemic stroke , cardiology , intensive care medicine , ischemia , mechanical engineering , stenosis , pathology , engineering
Prevention of early recurrent ischaemic stroke remains a priority in people with TIA or ischaemic stroke. A number of trials have recently been completed assessing the efficacy of short-term dual antiplatelet therapy (DAPT) versus single antiplatelet therapy early after minor or moderate stroke or high-risk TIA. We present an Expedited Recommendation for use of dual antiplatelet therapy early after ischaemic stroke and TIA on behalf of the ESO Guideline Board. We make a strong recommendation based on high quality of evidence for use of 21-days of dual antiplatelet therapy with aspirin and clopidogrel in people with a non-cardioembolic minor ischaemic stroke or high-risk TIA in the past 24 hours. We make a weak recommendation based on moderate quality evidence for 30-days of dual antiplatelet therapy with aspirin and ticagrelor in people with non-cardioembolic mild to moderate ischaemic stroke or high-risk TIA in the past 24 hours.