Open AccessPredicting Candida Infection in Pediatric Intensive Care Unit using Candida Score in a Low-Resource Setting
Author(s) -
Dicky Ari Risandy,
Desy Rusmawatiningtyas,
Firdian Makrufardi,
Elisabeth Siti Herini,
Nurnaningsih
Publication year - 2021
Publication title -
global pediatric health
Language(s) - English
Resource type - Journals
ISSN - 2333-794X
DOI - 10.1177/2333794x21999152
Subject(s) - medicine , candida infections , incidence (geometry) , pediatric intensive care unit , intensive care unit , confounding , candida albicans , invasive candidiasis , pediatrics , antifungal , fluconazole , microbiology and biotechnology , biology , physics , dermatology , optics
Candida infection was previously thought to be rare in intensive care. With the increased use of broad-spectrum antibiotics, the incidence of candida infection increased significantly. Case-control study was done in patients ≤18 years of age treated for 3 days or more in Pediatric Intensive Care Unit (PICU) Dr. Sardjito General Hospital, Yogyakarta from January 2014 to December 2016. Overall, 43 children were included in this study as a case group with positive candida culture and 43 children as a control group with no candida culture. Cut off point of candida score is ≥3 from our subjects. The area under curve (AUC) value for cut off ≥3 was moderate (0,72). Candida score ≥3 has an odd ratio (OR) 6.8 (95% CI 2.4-18.6) with P .05. Candida score can be used as predictor of candida infection in PICU.