EVALUATION OF CORRELATIONAL INFORMATION IN DIGITIZED CELL IMAGES
Author(s) -
Wayburn S. Jeter,
George B. Olson,
Peter H. Bartels,
G. F. Bahr,
John Taylor,
George L. Wied
Publication year - 1974
Publication title -
journal of histochemistry and cytochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 124
eISSN - 1551-5044
pISSN - 0022-1554
DOI - 10.1177/22.2.69
Subject(s) - curse of dimensionality , covariance , covariance matrix , pattern recognition (psychology) , artificial intelligence , representation (politics) , image (mathematics) , image processing , set (abstract data type) , computer science , mutual information , digital image , digital image processing , computer vision , mathematics , statistics , algorithm , politics , political science , law , programming language
The processing of digitized cell images by computer may yield information not only about a set of cell image properties but also about their mutual dependencies. Observation of the covariance matrix of image properties of cellular material showing a response to chemotherapeutic treatment, ionizing radiation or antigenic challenge or following a developmental trend may permit a quantitative description of small trendal charges The covariance between certain cell image properties may show statistically significant changes before the mean values of the image properties are affected. Methods of reducing the dimensionality of the representation in an efficient manner are described.
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