Suppository treatment in ulcerative proctitis
Author(s) -
Yingjie Si,
LanJun Shao,
Shanqing Gao,
Hong-Zhu Wen
Publication year - 2021
Publication title -
european journal of inflammation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.219
H-Index - 20
eISSN - 2058-7392
pISSN - 1721-727X
DOI - 10.1177/20587392211015108
Subject(s) - suppository , ulcerative colitis , medicine , adverse effect , budesonide , tofacitinib , gastroenterology , tacrolimus , pharmacology , corticosteroid , disease , transplantation , rheumatoid arthritis
Ulcerative proctitis (UP) is a common form of ulcerative colitis (UC), the number of patients with UP is increasing. Suppository treatment containing mesalamine is usually the first-line choice for mild to moderate UP, here, we review the publications on mesalamine suppository in UP, to better understand its dosage, duration of therapy and adverse events in both induction and maintenance phases. We also review articles on budesonide, beclomethasone, tacrolimus, herbal medicine and acetarsol suppositories in UP, to present therapeutic strategies for patients with UP refractory to mesalamine suppository.
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