Shrimp sensitization in house dust mite allergic patients
Author(s) -
Natalia Ukleja-Sokołowska,
Ewa Gawrońska-Ukleja,
Kinga Lis,
Magdalena Żbikowska-Götz,
Rafał Adamczak,
Łukasz Sokołowski,
Zbigniew Bartuzi
Publication year - 2020
Publication title -
international journal of immunopathology and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.724
H-Index - 53
eISSN - 2058-7384
pISSN - 0394-6320
DOI - 10.1177/2058738420907188
Subject(s) - shrimp , sensitization , allergy , house dust mite , pyroglyphidae , mite , medicine , allergen , dust mites , immunoglobulin e , immunology , biology , antibody , ecology
Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to and 57.8% to . In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable.
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