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Antifungal activity in the methanolic, aqueous and hexane extracts of Calligonum polygonoides
Author(s) -
Ahmad Saeed,
Akram Muhammad
Publication year - 2019
Publication title -
international journal of immunopathology and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.724
H-Index - 53
eISSN - 2058-7384
pISSN - 0394-6320
DOI - 10.1177/2058738418821275
Subject(s) - aspergillus niger , ethyl acetate , candida albicans , chemistry , hexane , traditional medicine , antifungal , minimum inhibitory concentration , aqueous solution , polygonaceae , chromatography , food science , microbiology and biotechnology , biochemistry , botany , in vitro , biology , organic chemistry , medicine
Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2.9, 6.5, 12.6, 25, 50 and 75 µg/mL/disc. Calligonum polygonoides showed significant activity against Candida albicans as the observed minimum inhibitory concentration (MIC) is 6.5 µg/mL for methanolic extract, 9.8 µg/mL for ethyl acetate extract, whereas aqueous and hexane extracts showed no activity. Calligonum polygonoides did not show any significant activity against Aspergillus niger.

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