Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome | Zendy

Naila Makhani | Zendy; Christine LebrunFrénay | Zendy; Aksel Sıva | Zendy; Sorula | Zendy; Evangeline Wassmer | Zendy; David Brassat | Zendy; J. Nicholas Brenton | Zendy; Philippe Cabre | Zendy; Clarisse CarraDallière | Zendy; de Sèze | Zendy; Françoise Durand Dubief | Zendy; Matilde Inglese | Zendy; Megan Langille | Zendy; Guillaume Mathey | Zendy; Rinze F. Neuteboom | Zendy; Jean Pelletier | Zendy; Daniela Pohl | Zendy; Daniel S. Reich | Zendy; Juan Ignacio Rojas | Zendy; Veronika Shabanova | Zendy; Eugene D. Shapiro | Zendy; Robert T Stone | Zendy; Sílvia Tenembaum | Zendy; Mar Tintoré | Zendy; Uğur Uygunoğlu | Zendy; Wendy Vargas | Zendy; Sunita Venkateswaren | Zendy; Patrick Vermersch | Zendy; Orhun H. Kantarci | Zendy; Darin T. Okuda | Zendy; Daniel Pelletier | Zendy

Open Access

Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome

Author(s) -

Naila Makhani,

Christine LebrunFrénay,

Aksel Sıva,

Sorula,

Evangeline Wassmer,

David Brassat,

J. Nicholas Brenton,

Philippe Cabre,

Clarisse CarraDallière,

de Sèze,

Françoise Durand Dubief,

Matilde Inglese,

Megan Langille,

Guillaume Mathey,

Rinze F. Neuteboom,

Jean Pelletier,

Daniela Pohl,

Daniel S. Reich,

Juan Ignacio Rojas,

Veronika Shabanova,

Eugene D. Shapiro,

Robert T Stone,

Sílvia Tenembaum,

Mar Tintoré,

Uğur Uygunoğlu,

Wendy Vargas,

Sunita Venkateswaren,

Patrick Vermersch,

Orhun H. Kantarci,

Darin T. Okuda,

Daniel Pelletier

Publication year - 2019

Publication title -

multiple sclerosis journal - experimental translational and clinical

Language(s) - English

Resource type - Journals

ISSN - 2055-2173

DOI - 10.1177/2055217319836664

Subject(s) - magnetic resonance imaging , medicine , multiple sclerosis , cerebrospinal fluid , clinically isolated syndrome , confidence interval , prospective cohort study , mcdonald criteria , radiology , pathology , immunology

Oligoclonal bands increased the specificity of magnetic resonance imaging criteria in children with Ped-RIS. Clinicians should consider testing cerebrospinal fluid to improve diagnostic certainty. There is rationale to include cerebrospinal fluid analysis for biomarkers including oligoclonal bands in planned prospective studies to develop optimal diagnostic criteria for radiologically isolated syndrome in children.

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