Open AccessSevere thrombocytopenia after Vaxzevria vaccination in a single patient: A case report
Author(s) -
Rehab Y Al-Ansari,
Faisal Hani Al Qahtany,
Yasmin A Qomawi,
Tawasoul Fadoul,
Alexander Woodman
Publication year - 2022
Publication title -
sage open medical case reports
Language(s) - English
Resource type - Journals
ISSN - 2050-313X
DOI - 10.1177/2050313x221091407
Subject(s) - medicine , vaccination , platelet , antibody , pediatrics , surgery , immunology
AstraZeneca vaccine became one of the four vaccines that encode different forms of the SARS-CoV-2 spike glycoprotein. We report the case of an 18-year-old medically free female with progressive bruising of the upper and lower extremities for 1 week, beginning 3 days after the first dose of AstraZeneca. Laboratory results showed severe thrombocytopenia of 4.3 × 10 3 /µL with a normal white blood cell count, renal profile, and hemolytic markers. She was treated conservatively with high-dose steroids and intravenous immunoglobulin, which resulted in a full recovery of her platelet count. In our case, the question was raised about the possibility of receiving a second dose of another vaccine product instead of not being vaccinated again, a subject for further research.