Open AccessIron deficiency in pulmonary arterial hypertension: perspectives
Author(s) -
Quatredeniers Marceau,
Montani David,
CohenSolal Alain,
Perros Frédéric
Publication year - 2021
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.1177/20458940211021301
Subject(s) - medicine , pulmonary hypertension , right heart failure , cardiology , heart failure , iron deficiency , anemia , first line , iron deficiency anemia
In left heart failure, iron supplementation (IS) is a first‐line treatment option, regardless of anemia. Pulmonary arterial hypertension (PAH), a rare disease leading to right heart failure, is also associated with iron deficiency. While it is a much debated topic, recent evidence demonstrate that restoration of iron stores results in improved right ventricular function and exercise tolerance. Hence, IS may also be considered as an option in the treatment of PAH.