Open AccessFlow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension
Author(s) -
Richter Manuel J.,
Harutyunova Satenik,
Bollmann Tom,
Classen Simon,
Fuge Jan,
Gall Henning,
Gerhardt Felix,
Ghofrani Hossein A.,
Gunkel Hartmut,
Grünig Ekkehard,
Halank Michael,
Heine Alexander,
Klose Hans,
Lange Tobias J.,
Neurohr Claus,
Nickolaus Kai,
Opitz Christian F.,
Rosenkranz Stephan,
Seyfarth HansJürgen,
Tello Khodr,
Ewert Ralf,
Olsson Karen M.
Publication year - 2020
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.1177/2045894020910136
Subject(s) - treprostinil , medicine , pulmonary hypertension , anesthesia , cardiology
Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.