Open AccessNovel imaging approaches for small animal models of lung disease (2017 Grover Conference series)
Author(s) -
Pinar Isaac P.,
Jones Heather D.
Publication year - 2018
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.1177/2045894018762242
Subject(s) - medicine , lung , lung disease , animal model , pathology , medical imaging , preclinical imaging , molecular imaging , radiology , in vivo , biology , microbiology and biotechnology
Imaging in small animal models of lung disease is challenging, as existing technologies are limited either by resolution or by the terminal nature of the imaging approach. Here, we describe the current state of small animal lung imaging, the technological advances of laboratory‐sourced phase contrast X‐ray imaging, and the application of this novel technology and its attendant image analysis techniques to the in vivo imaging of the large airways and pulmonary vasculature in murine models of lung health and disease.