Open AccessIncreased mortality from complications of pulmonary hypertension in patients undergoing transcatheter aortic valve replacement
Author(s) -
Parikh Raj,
Varghese Benson,
Khatoon Huma N.,
Kovach Julie A.,
Kavinsky Clifford J.,
Tandon Rajive
Publication year - 2017
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.1177/2045893217697709
Subject(s) - medicine , afterload , valve replacement , cardiology , ventricle , acute kidney injury , stenosis , pulmonary hypertension , atrioventricular block , aortic valve stenosis , surgery
Aortic stenosis (AS) leads to pulmonary hypertension (PH) and right ventricle (RV) failure. Our goal was to describe mortality related to postoperative complications in PH patients undergoing transcatheter aortic valve replacement (TAVR). Ninety‐three TAVR patients were analyzed (controls, sPAP < 50 mmHg; cases, sPAP ≥ 50 mmHg). Significant findings in cases included increased mortality (365 days), post‐TAVR atrioventricular block (AVB) and acute kidney injury (AKI), and increased mean length of stay (LOS). This novel study highlights complications of PH as independent risk factors for death and significant morbidity post TAVR. Optimization of preoperative volume status and RV afterload reduction, while addressing AVB and AKI, may play a vital role in reducing mortality and LOS.