Open AccessPancreatic metastases and first reported gallbladder metastasis from phyllodes tumor of the breast
Author(s) -
Salsabil Nasri,
Fehmi Hamila,
Rym Bourigua,
S Mestiri,
Mohamed Amine Elghali
Publication year - 2020
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.1177/2036361320972866
Subject(s) - medicine , malignancy , metastasis , gallbladder , radiology , pancreatic tumor , radical mastectomy , lung , modified radical mastectomy , right breast , adjuvant chemotherapy , epigastric pain , breast cancer , mastectomy , general surgery , oncology , pancreatic cancer , cancer , vomiting
Distant metastases from breast phyllodes tumor (PT) are very rare. They usually occur in lung and bones. We report a case of a 51-year-old woman who was hospitalized in the digestive surgical department for atypical epigastric pain. Her medical history started 2 years ago when she underwent a curative left mastectomy for a malignant PT of the breast. Radical surgery was indicated to her resectable pancreatic tumor diagnosed on computed tomography. Histological exam confirmed that it was pancreatic metastases of her breast PT. Adjuvant chemotherapy was indicated. Three months after the surgery, the patient developed gallbladder and brain metastases. She died 5 weeks later. With this case, we enrich the literature with another example of pancreatic metastasis from PT and we report, for the first time, gallbladder metastasis. The very high aggressiveness of this tumor suggests that markers of tumor malignancy need to be sought after by subsequent studies.