THE IMMUNOCYTOCHEMICAL DEMONSTRATION OF CATHEPSIN D | Zendy

A. R. Poole | Zendy; J. T. Dingle | Zendy; A. John Barrett | Zendy

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THE IMMUNOCYTOCHEMICAL DEMONSTRATION OF CATHEPSIN D

Author(s) -

A. R. Poole,

J. T. Dingle,

A. John Barrett

Publication year - 1972

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/20.4.261

Subject(s) - immunocytochemistry , organelle , cytoplasm , lysosome , cathepsin d , cathepsin , microbiology and biotechnology , epithelium , pathology , fluorescence microscope , cathepsin b , chemistry , biology , enzyme , fluorescence , medicine , biochemistry , physics , quantum mechanics

Cathepsin D has been demonstrated for the first time using an immunocytochemical approach and fluorescence microscopy. It has been localized in chick epithelium-like cells and in cells of synovia from joints of rabbits with an experimental arthritis. The enzyme is associated with lysosome-like organelles: it also has a diffuse cytoplasmic distribution in these cells.

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