DISTRIBUTION OF GLYCOGEN WITHIN THE LIVER LOBULE | Zendy

Frank A. Welsh | Zendy

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DISTRIBUTION OF GLYCOGEN WITHIN THE LIVER LOBULE

Author(s) -

Frank A. Welsh

Publication year - 1972

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/20.2.112

Subject(s) - glycogen , medicine , endocrinology , lobules of liver , cortisone , staining , chemistry , biology , pathology

Quantitative determinations of glycogen of periportal and centrilobular cells of the liver were made in normal, fasted, realimented and cortisone-treated rats. In most instances there was no significant portal-central difference in glycogen concentration. There were two exceptions. After 2 hr of refeeding following a 24-hr fast, the central to portal glycogen ratio was 1.3. During recovery from the glycogen overshoot, which occurs upon feeding after a prolonged fast, portal glycogen exceeded central glycogen by a factor of 1.8. It is suggested that some of the discordant staining findings on glycogen distribution arise from artifacts.

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