Chemical Composition and Enzyme Inhibitory Activities of Turkish  Pancratium maritimum  Bulbs | Zendy

Bozkurt Buket | Zendy; Kaya Gulen I. | Zendy; Somer Nehir U. | Zendy

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Chemical Composition and Enzyme Inhibitory Activities of Turkish Pancratium maritimum Bulbs

Author(s) -

Bozkurt Buket,

Kaya Gulen I.,

Somer Nehir U.

Publication year - 2019

Publication title -

natural product communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.221

H-Index - 44

ISSN - 1555-9475

DOI - 10.1177/1934578x19872905

Subject(s) - amaryllidaceae , butyrylcholinesterase , lycorine , oligopeptidase , chemistry , moraceae , alkaloid , amaryllidaceae alkaloids , acetylcholinesterase , bulb , botany , traditional medicine , aché , enzyme , stereochemistry , biology , biochemistry , medicine

The chemical composition of the bulbs of Pancratium maritimum L. (Amaryllidaceae) from Turkey (Pamucak, Aydın) has been determined by gas chromatography-mass spectrometry. A total of 29 compounds belonging to different skeletal types of Amaryllidaceae alkaloids were identified. Lycorine, galanthamine, crinine, and pancracine were found as major constituents. Interestingly, indole alkaloids (1-acetyl-β - carboline and galanthindole) were also detected. Acetylcholinesterase, butyrylcholinesterase, and prolyl oligopeptidase inhibitory activity potentials of the alkaloidal extract were also determined. The results of the present study show that Turkish P. maritimum comprises a rich repository for bioactive alkaloids with intriguing structural diversities.

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