Antiproliferative Oleanane Saponins from Dizygotheca Elegantissima | Zendy

Antonio Vassallo | Zendy; Mariasabina Pesca | Zendy; Letizia Ambrosio | Zendy; Nicola Malafronte | Zendy; Nadia Dekdouk Melle | Zendy; Fabrizio Dal Piaz | Zendy; Lorella Severino | Zendy

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Antiproliferative Oleanane Saponins from Dizygotheca Elegantissima

Author(s) -

Antonio Vassallo,

Mariasabina Pesca,

Letizia Ambrosio,

Nicola Malafronte,

Nadia Dekdouk Melle,

Fabrizio Dal Piaz,

Lorella Severino

Publication year - 2012

Publication title -

natural product communications

Language(s) - English

Resource type - Journals

eISSN - 1934-578X

pISSN - 1555-9475

DOI - 10.1177/1934578x1200701106

Subject(s) - oleanane , two dimensional nuclear magnetic resonance spectroscopy , chemistry , heteronuclear single quantum coherence spectroscopy , stereochemistry , nuclear magnetic resonance spectroscopy , saponin , triterpene , medicine , alternative medicine , pathology

Four new oleanane saponins (1-4), together with three known saponins, were isolated from the aerial parts of Dizygotheca elegantissima R. Vig. & Guillaumin. Their structures were elucidated by 1D and 2D NMR experiments including 1D TOCSY, DQF-COSY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all isolated compounds was evaluated.

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