Open AccessConstituents of ‘Caincin’, a Bioactive Saponin Fraction from the Root-bark of Chiococca alba (L.) Hitch
Author(s) -
Jnanabrata Bhattacharyya,
Swati Srivastava,
María F. Agra,
George Majetich
Publication year - 2008
Publication title -
natural product communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.221
H-Index - 44
eISSN - 1934-578X
pISSN - 1555-9475
DOI - 10.1177/1934578x0800300916
Subject(s) - saponin , chemistry , rubiaceae , bark (sound) , traditional medicine , terpene , fraction (chemistry) , ethyl acetate , triterpenoid saponin , stereochemistry , botany , organic chemistry , biology , medicine , alternative medicine , ecology , pathology
‘Caincin’, a bioactive saponin mixture from Chiococca alba (L.) Hitch. (Rubiaceae), first obtained by European workers in nineteenth century and which was thought to be a homogenous material, was investigated by us and resulted in the isolation of three saponins characterized as 3β-[(β-D-glucuronopyranosyl)oxy]-oleana-12,15-dien-28-oic acid, 3β-[(β-D-glucuronopyranosyl)oxy]-oleana-12,15-dien-28-oic acid 6′-ethyl ester, and 3β-[(β-D-glucuronopyranosyl)oxy]-23-hydroxyoleana-12,15-dien-28-oic acid 6′- ethyl ester.
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