Clostridium Perfringens Bacteremia with Acute Hemolytic Anemia in the Setting of Endometrial Malignancy | Zendy

Cypher Luke R. | Zendy; Sullivan Christopher | Zendy; Jones Ryan | Zendy; Phillips Angelina | Zendy

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Clostridium Perfringens Bacteremia with Acute Hemolytic Anemia in the Setting of Endometrial Malignancy

Author(s) -

Cypher Luke R.,

Sullivan Christopher,

Jones Ryan,

Phillips Angelina

Publication year - 2019

Publication title -

academic forensic pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.256

H-Index - 11

ISSN - 1925-3621

DOI - 10.1177/1925362119851240

Subject(s) - clostridium perfringens , gas gangrene , hemolysis , bacteremia , malignancy , medicine , clostridium septicum , disseminated intravascular coagulation , hemolytic anemia , gastroenterology , microbiology and biotechnology , immunology , surgery , biology , antibiotics , bacteria , genetics

Acute intravascular hemolysis is a rare and often lethal complication of Clostridium perfringens septicemia.Clostridium perfringens is an anaerobic, gram-positive spore-forming rod which is commonly implicated in cases of food poisoning, gas gangrene, and severe hemolytic anemia in humans via the alpha-toxin (phospholipase C). We report an interesting and rare case of a 72-year-old woman who developed massive intravascular hemolysis secondary to C perfringens bacteremia in the setting of poorly differentiated high-grade endometrial malignancy.

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