SUBPOPULATIONS OF BLOOD LYMPHOCYTES DEMONSTRATED BY QUANTITATIVE CYTOCHEMISTRY | Zendy

F Giacomelli | Zendy; Joseph Wiener | Zendy; Joanna V. Pomeranz | Zendy; Alden V. Loud | Zendy; Joseph B. Kruskal | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SUBPOPULATIONS OF BLOOD LYMPHOCYTES DEMONSTRATED BY QUANTITATIVE CYTOCHEMISTRY

Author(s) -

F Giacomelli,

Joseph Wiener,

Joanna V. Pomeranz,

Alden V. Loud,

Joseph B. Kruskal

Publication year - 1971

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1177/19.7.426

Subject(s) - cytochemistry , glutaraldehyde , bimodality , pathology , cell , blood cell , chemistry , biology , biophysics , ultrastructure , immunology , anatomy , physics , biochemistry , medicine , quantum mechanics , galaxy

The cell coats of glutaraldehyde-fixed blood lymphocytes from guinea pigs have been stained with Thorotrast and examined by electron microscopy. The lymphocytes have been classified into three groups with respect to the concentration and distribution of colloidal particles over their surfaces. The average number of particles per micron length of cell surface membrane, the particle density, has then been measured for each class of cells. These values are distributed into two clusters separated by a gap. A new statistical test for bimodality has been devised to evaluate the significance of such a gap in terms of its "dip intensity." The results of this analysis demonstrate the existence of at least two distinct populations of blood lymphocytes, indistinguishable by other morphologic criteria.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research