Effect of menopausal hormone therapy on components of the metabolic syndrome
Author(s) -
Dragana Lovre,
Sarah H. Lindsey,
Franck MauvaisJarvis
Publication year - 2016
Publication title -
therapeutic advances in cardiovascular disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 33
eISSN - 1753-9455
pISSN - 1753-9447
DOI - 10.1177/1753944716649358
Subject(s) - medicine , metabolic syndrome , dyslipidemia , menopause , lifestyle modification , type 2 diabetes , obesity , hormone therapy , endocrinology , diabetes mellitus , hormone replacement therapy (female to male) , hormone , bioinformatics , physiology , testosterone (patch) , cancer , biology , breast cancer
The world population is aging, and women will spend an increasing share of their lives in a postmenopausal state that predisposes to metabolic dysfunction. Thus, the prevalence of metabolic syndrome (MetS) in women is likely to increase dramatically. This article summarizes the effects of menopause in predisposing to components of MetS including visceral obesity, dyslipidemia, type 2 diabetes (T2D) and hypertension (HTN). We also summarize the effects of menopausal hormone therapy (MHT) in reversing these metabolic alterations and discuss therapeutic advances of novel menopausal treatment on metabolic function.
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